Objective To construct a program for elderly patients with polypharmacy after percutaneous coronary intervention，and to ensure the safety of patients’ polypharmacy throughout the process. Methods Based on evidence-based methods to retrieve domestic and foreign literature，and guided by the 4R crisis management theory，the first draft of the medication management program was formulated by the research group，and the final program was revised and established according to the experts’ opinions by Delphi method from January to July 2022. Results 15 experts participated in 2 rounds of consultations，and the effective recovery rate of questionnaire was 100%. The expert authority scores of 2 rounds were 0.90，and the importance and operability of the second round of expert opinions Kendall harmony were 0.216 and 0.289. The final program contained 4 primary indicators，7 secondary indicators and 23 tertiary indicators. Conclusion The constructed medication management program for elderly patients with polypharmacy after percutaneous coronary intervention is scientific and comprehensive，which can provide a theoretical basis and practical direction for the management of patients.

Objective To investigate the relationship between the changes of blood pressure and palmar swelling during radial artery compression in patients with radial artery percutaneous coronary intervention (PCI). Methods The patients who underwent radial artery PCI in the coronary heart disease unit of a tertiary general hospital in Nanchang from May 2018 to December 2020 were selected as the study subjects. The general data and the related indexes of decompression were analyzed retrospectively,and the blood pressure fluctuation during radial artery compression was described. Univariate regression analysis was used to analyze the influencing factors of palmar swelling on the operative side,and the blood pressure during radial artery compression was divided into nodes. The effects of different blood pressure on operative side palm swelling were analyzed by stratification,and the corresponding range of blood pressure at the highest risk of operation side palm swelling was further analyzed by trend regression. Results A total of 788 patients with radial artery PCI were included. Based on the analysis of patients’ baseline data,it was found that history of diabetes,history of hypertension,signs of heart failure and high average systolic blood pressure during radial artery compression were the risk factors of operative palmar swelling. However,multivariate stratified analysis of risk factors showed that systolic blood pressure ≥130 mmHg during radial artery compression increased the risk of ipsilateral palm swelling in patients with diabetic history (OR=1.09,P<0.001). In patients with or without heart failure signs and hypertension history,when the systolic blood pressure during radial artery compression was more than 130 mmHg,the 2 groups increased the risk of palmar swelling on the operative side. Furthermore,trend regression analysis showed that the average systolic blood pressure during radial artery compression was between 130 and 149 mmHg. Every 10 mmHg increase in systolic blood pressure had increased the risk of palmar swelling by 3.52 times[95%CI (1.37,13.22) ]. Conclusion During the period of radial artery compression,the average systolic blood pressure of patients is 130-149 mmHg,and the risk of palmar swelling on the operative side is the highest. It is suggested that clinical nurses should comprehensively consider the changes of systolic blood pressure when formulating the prevention plan for complications of palmar swelling on the operative side.